What is Elahere?
Elahere is a prescription medicine used to treat adults with folate receptor-alpha positive ovarian cancer, fallopian tube cancer, or primary peritoneal cancer who:
- have not responded to or are no longer responding to treatment with platinum-based chemotherapy and
- have received 1 to 3 prior types of chemotherapy.
Your healthcare provider will perform a test to make sure that Elahere is right for you.
It is not known if Elahere is safe and effective in children.
What is the most important information I should know about Elahere?
Elahere can cause serious side effects, including:
- Eye problems. Eye problems are common with Elahere and can also be severe. Tell your healthcare provider right away if you develop any eye problems during treatment with Elahere, including blurred vision, dry eyes, sensitivity to light, eye pain, or new or worsening vision changes.
- Your healthcare provider will send you to see an eye care professional to check your eyes before you start treatment with Elahere, during treatment with Elahere, and as needed for any worsening signs and symptoms of eye problems.
- Your healthcare provider will prescribe steroid eye drops and lubricating eye drops before you start and during your treatment with Elahere. You should use eye drops as directed by your healthcare provider.
- Do not wear contact lenses throughout your treatment with Elahere unless you are told to use them by your healthcare provider.
See "What are the possible side effects of Elahere?" for more information about side effects.
What should I tell my healthcare provider before using Elahere?
Before receiving Elahere, tell your healthcare provider about all of your medical conditions, including if you:
- have vision or eye problems.
- have liver problems.
- are pregnant or plan to become pregnant. Elahere can harm your unborn baby. Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with Elahere.
Females who are able to become pregnant:- Your healthcare provider should do a pregnancy test before you start treatment with Elahere.
- You should use an effective birth control (contraception) during treatment and for 7 months after your last dose of Elahere.
- are breastfeeding or plan to breastfeed. It is not known if Elahere passes into your breast milk. Do not breastfeed during treatment and for 1 month after your last dose of Elahere.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Taking certain other medicines during treatment with Elahere may cause side effects.
How should I use Elahere?
- Elahere will be given to you by infusion into your vein (intravenous or IV).
- Before each dose of Elahere you will receive medicines to help prevent infusion related reactions, nausea, and vomiting.
- Elahere is usually given every 3 weeks (21-day cycle). Your healthcare provider will decide how many cycles you need.
What are the possible side effects of Elahere?
Elahere can cause serious side effects, including:
- See "What is the most important information I should know about Elahere?"
- Lung problems (pneumonitis). Elahere can cause severe or life-threatening inflammation of the lungs that may lead to death. Tell your healthcare provider right away if you get new or worsening symptoms, including trouble breathing, shortness of breath, cough, or chest pain.
- Peripheral neuropathy. You may develop nerve problems called peripheral neuropathy during treatment with Elahere. Your healthcare provider will monitor you for signs and symptoms of nerve problems. Tell your healthcare provider if you get new or worsening numbness or tingling in your hands or feet or muscle weakness.
The most common side effects of Elahere include:
- feeling tired
- increased liver enzymes in the blood
- nausea
- stomach-area (abdominal) pain
- decreased red or white blood cell counts
- diarrhea
- decreased albumin level in the blood
- constipation
- decreased magnesium level in the blood
Your healthcare provider may change your dose of Elahere, delay treatment, or completely stop treatment if you have certain side effects.
These are not all of the possible side effects of Elahere.
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
General information about the safe and effective use of Elahere
Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. If you would like more information about Elahere, talk with your healthcare provider. You can ask your pharmacist or healthcare provider for information about Elahere that is written for healthcare professionals.
What are the ingredients in Elahere?
Active ingredient: mirvetuximab soravtansine-gynx
Inactive ingredients: glacial acetic acid, polysorbate 20, sodium acetate, sucrose, Water for Injection.
For more information, go to www.immunogen.com or call 1-833-486-4646.
