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NitroMist

Generic name: nitroglycerin

What is NitroMist used for?

  • NitroMist is used to treat or prevent chest pain or pressure.
  • NitroMist may be given to you for other reasons. Talk to your doctor.

Before taking NitroMist, tell your doctor:

  • If you are allergic to NitroMist; any part of this medicine; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
  • If you have any of these health problems: Anemia, raised pressure in the head (like with bleeding in the brain or head injury), or recent heart attack.
  • If you have heart problems.
  • If you have low blood volume.
  • If you are taking any of these drugs: Avanafil, riociguat, sildenafil, tadalafil, or vardenafil.
  • If you are taking any of these drugs: Dihydroergotamine, ergonovine, ergotamine, or methylergonovine.

This is not a list of all drugs or health problems that interact with this medicine.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take NitroMist with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take NitroMist?

  • Tell all of your health care providers that you take NitroMist. This includes your doctors, nurses, pharmacists, and dentists.
  • Avoid driving and doing other tasks or actions that call for you to be alert or have clear eyesight until you see how NitroMist affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Be careful going up and down stairs.
  • Check your blood pressure as you have been told.
  • This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take NitroMist.
  • Avoid drinking alcohol while taking NitroMist.
  • If you are 65 or older, use NitroMist with care. You could have more side effects.
  • Taking more of NitroMist or taking it more often than you have been told may cause it to not work as well. This is known as tolerance. Talk with your doctor if NitroMist stops working well. Do not take more than ordered.
  • Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.

How is NitroMist best taken?

Use NitroMist as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Prime pump before first use.
  • Some products may have different ways to prime the pump. Some pumps may also need to be primed if not used for different periods of time. Follow how and when to prime as you have been told.
  • Sit down before use.
  • Do not shake.
  • Spray on or under tongue.
  • Avoid swallowing after use.
  • Avoid rinsing mouth for 5 to 10 minutes after use.
  • Check how much fluid is left in the pump on a regular basis. Be sure you know when you need to get a refill.
  • This medicine may catch on fire. Do not use near an open flame or while smoking.
  • Your doctor will tell you how to take NitroMist. Be sure you know what your dose is, how often you can take a dose, and when you may need to get medical help. If your doctor does not tell you how to take NitroMist or if you are not sure how to take it, talk with your doctor.
  • If using NitroMist to prevent chest pain, use it 5 to 10 minutes before activity that may lead to chest pain.

What do I do if I miss a dose?

  • This medicine is taken on an as needed basis. Do not take more often than told by the doctor.

What are the side effects of NitroMist that I need to call my doctor about immediately?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Very bad dizziness or passing out.
  • Fast, slow, or abnormal heartbeat.
  • Flushing.
  • Blurred eyesight.
  • Dry mouth.
  • Sweating a lot.
  • Pale skin.
  • Very upset stomach or throwing up.
  • Restlessness.
  • Feeling very tired or weak.

What are some other side effects of NitroMist?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Dizziness or headache.
  • Mouth tingling.
  • Burning.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If overdose is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out NitroMist?

  • Store at room temperature in a dry place. Do not store in a bathroom.
  • Protect from heat or open flame. Do not puncture or burn even if it seems empty.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer information use and disclaimer

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about NitroMist, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take NitroMist or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to NitroMist. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Source: Wolters Kluwer Health. Last updated April 5, 2023.